Building Gram Positive and Gram Negative Cell Walls

Time to complete course: 15 min.

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About Building Gram Positive and Gram Negative Cell Walls Virtual Lab Simulation

This short, targeted simulation is adapted from the full-length “The Gram Stain: Identify and differentiate bacteria” simulation.

Did you know that there are approximately 5 million-trillion-trillion bacteria in the world? Most of them are harmless, some are the cause of serious diseases, but all of them are either Gram positive or Gram negative bacteria. In this simulation, you will explore the structure of bacterial cell walls and learn how to recognise them.    

Explore cell wall structures

Discover different structures that build up both types of cell walls and familiarize yourself with their functions. What are the real differences between Gram positive and negative bacteria?

Build your own 3D models

Compare and contrast the cell wall of Gram-positive and Gram-negative bacteria. Play around at the holotable and see if you can replicate the structure of both groups. Test your knowledge on their structures by building your very own bacterial 3D models on the hologram table. Will you be the next Gram and discover a completely new group of bacteria?

Get Started Now

Have you ever wondered what exactly makes bacteria divided into Gram groups? Do they have special barcodes or tiny identifiers at their surface? Let’s find out together!

Techniques in Lab

  • Concept-based simulation

Learning Objectives

  • Differentiate between gram-positive and gram-negative cell walls
  • Relate the structure of bacterial cell envelopes to Gram stain outcomes

Simulation Features

Length – 15 minutes
Accessibility mode – Available
Languages – English, French, German, Spanish, Italian

Examples of Related Standards


Microbiology related 1st year




Biology 1.3: Membrane Structure
Biology 6.3: Defence from infectious disease


Biology Unit 2: Cell structure and function

Screenshots of Building Gram Positive and Gram Negative Cell Walls Virtual Lab Simulation


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